BACKGROUND, Few reports have estimated the prevalence of persons in th
e U.S. ever diagnosed with invasive cancer. METHODS, The Connecticut T
umor Registry was used to identify all Connecticut residents ever diag
nosed (1935-1994) with invasive cancer who were known to be alive in 1
994. Estimated prevalence rates for Connecticut were compared with tho
se for 1982, and were applied to the total U.S. population for selecte
d years. RESULTS, Some 95,361 persons ever diagnosed with invasive can
cer(s) were confirmed as being alive at the end of 1994. The age-stand
ardized prevalence rate had increased by 40% in males and 13% in femal
es since 1982, due in part to large increases for breast, prostate, an
d (in females) lung carcinoma. Using the data for Connecticut, an esti
mated 7.1 million Americans in 1995 had ever been diagnosed with invas
ive cancer; projected numbers were 7.7 million for 2000 and 13.2 milli
on for 2030. CONCLUSIONS. The prevalence of persons ever diagnosed wit
h invasive cancer could increase considerably in the coming decades, a
nd numbers for elderly males could surpass those for elderly females b
y 2020. Although projections must be interpreted with caution, these d
ata emphasize the need for primary prevention of cancer and for studie
s of cancer survivors. (C) 1997 American Cancer Society.