Introduction: Serous cystadenomas of the pancreas are rare tumors and thoug
ht to be almost always benign. Methods: We report our experience in the dia
gnosis and surgical treatment of 12 patients with these tumors. Results: Be
tween October 1993 and December 1998, 41 patients with cystic tumors of the
pancreas underwent surgical resection; in 12 cases (11 women, 1 man) a ser
ous cystadenoma (10 microcystic, 2 oligomacrocystic) was found. Only 6 (50%
) patients had symptoms. The mean tumor size was 4.8 (2.7-10) cm. Ultrasoun
d, CT and MRT usually could detect the mass, but differentiation with other
cystic lesions was not reliable. All tumors were resected: 4 Whipple proce
dures, 7 distal pancreatectomies and 1 segmental resection were performed.
No patient died after surgery and none had to be reoperated on. Conclusions
: Because of the difficulty in reliably differentiating benign and malignan
t lesions of the pancreas, we believe that cystic tumors of the pancreas sh
ould be resected.