Noninvasive monitoring of nonshunted pulmonary capillary blood flow in theacute respiratory distress syndrome

Citation
Kjk. Kanhai et al., Noninvasive monitoring of nonshunted pulmonary capillary blood flow in theacute respiratory distress syndrome, CRIT CARE M, 28(4), 2000, pp. 1059-1067
Citations number
34
Categorie Soggetti
Aneshtesia & Intensive Care
Journal title
CRITICAL CARE MEDICINE
ISSN journal
00903493 → ACNP
Volume
28
Issue
4
Year of publication
2000
Pages
1059 - 1067
Database
ISI
SICI code
0090-3493(200004)28:4<1059:NMONPC>2.0.ZU;2-I
Abstract
Objective: Noninvasive monitoring of nonshunted pulmonary capillary blood f low, using the alveolar amplitude response technique (AART) in a porcine mo del of the acute respiratory distress syndrome. Design: Experimental animal study Setting: University center for animal experiments Interventions: In 12 mechanically ventilated pigs, the nonshunted pulmonary capillary blood flow was varied by means of lung lavages and the applicati on of positive end-expiratory pressure, Measurements and Main Results: Nonshunted pulmonary capillary blood flow wa s determined by AART, Cardiac output (determined by the thermodilution meth od) corrected for venous admixture was used for comparison (r(2) varied bet ween .58 and .94; p <.01), The trend in the development of nonshunted pulmo nary capillary blood flow as measured with AART was in agreement with the t rend detected by cardiac output corrected for venous admixture in 92% of al l events. Conclusions: We conclude that AART can be used to monitor changes in nonshu nted pulmonary capillary blood flow in cases of acute respiratory distress syndrome noninvasively and continuously.