The main purpose of this study was to evaluate the long term effects of uni
lateral dense central corneal scars on the axial length and development of
lens opacities. We included 12 patients with unilateral dense central corne
al scars of early onset before the age of seven years. This study served as
naturally-controlled experiment and demonstrated a statistically significa
nt increase in ocular axial length and decrease in the incidence of catarac
t in the eye with central corneal scar. Visual deprivation induced by unila
teral central corneal scars occurring in early childhood leads to increase
in the ocular axial length, and decrease in the incidence of cataract.