Distribution of the meningococcal insertion sequence IS1301 in clonal Lineages of Neisseria meningitidis

Authors
Hilse, R Stoevesandt, J Caugant, DA Claus, H Frosch, M Vogel, U
Citation
R. Hilse et al., Distribution of the meningococcal insertion sequence IS1301 in clonal Lineages of Neisseria meningitidis, EPIDEM INFE, 124(2), 2000, pp. 337-340
Citations number
12
Categorie Soggetti
Medical Research General Topics
Journal title
EPIDEMIOLOGY AND INFECTION
ISSN journal
09502688 → ACNP
Volume
124
Issue
2
Year of publication
2000
Pages
337 - 340
Database
ISI
SICI code
0950-2688(200004)124:2<337:DOTMIS>2.0.ZU;2-0
Abstract
The distribution of the meningococcal insertion sequence IS1301 was analyse d in 496 strains of different serogroups and clonal lineages of Neisseria m eningitidis, and in 64 neisserial strains other than N. meningitidis. IS130 1 was found in meningococci, but not in apathogenic Neisseria sp. and Neiss eria gonorrhoeae. The copy numbers of IS1301 varied between 2 and 17 per ge nome. IS1301 positive strains were mostly found among the serogroups 29E, W 135, X, and Y. Clonal lineages of serogroup A, B, and C meningococci associ ated with epidemic meningococcal disease were rarely positive for IS1301.