Remote anisotropic effects in diastereomeric esters of fluorinated O-aryllactic acids

Authors
Gras, JL Soto, T Heumann, A
Citation
Jl. Gras et al., Remote anisotropic effects in diastereomeric esters of fluorinated O-aryllactic acids, EUR J ORG C, (5), 2000, pp. 837-840
Citations number
20
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
ISSN journal
1434193X → ACNP
Issue
5
Year of publication
2000
Pages
837 - 840
Database
ISI
SICI code
1434-193X(200003):5<837:RAEIDE>2.0.ZU;2-M
Abstract
The enantiomeric purity of a chiral compound is determined by NMR spectrosc opic analysis of the diastereomers formed with a chiral derivatizing agent. Fluorinated O-aryllactic acids (FAC) 1 are efficient chiral reporters, who se spectacular remote anisotropic effects allow an easy identification and measurement of diastereomers. The remote effects are attributed to the part icular design of FAC esters relative to other CDAs.