The S-thioester enolate/imine condensation: A shortcut to beta-lactams

Authors
Benaglia, M Cinquini, M Cozzi, F
Citation
M. Benaglia et al., The S-thioester enolate/imine condensation: A shortcut to beta-lactams, EUR J ORG C, (4), 2000, pp. 563-572
Citations number
67
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
ISSN journal
1434193X → ACNP
Issue
4
Year of publication
2000
Pages
563 - 572
Database
ISI
SICI code
1434-193X(200002):4<563:TSECAS>2.0.ZU;2-L
Abstract
The condensation between imines and Sthioester metal enolates provides a mi ld, efficient, and straightforward route to the preparation of beta-lactams . The synthetic applications and the stereochemical aspects of this reactio n are discussed.