External validation of the Templeton model for predicting success after IVF

Citation
Jmj. Smeenk et al., External validation of the Templeton model for predicting success after IVF, HUM REPR, 15(5), 2000, pp. 1065-1068
Citations number
12
Categorie Soggetti
Reproductive Medicine","da verificare
Journal title
HUMAN REPRODUCTION
ISSN journal
02681161 → ACNP
Volume
15
Issue
5
Year of publication
2000
Pages
1065 - 1068
Database
ISI
SICI code
0268-1161(200005)15:5<1065:EVOTTM>2.0.ZU;2-B
Abstract
This study aimed to externally validate the prognostic model presented by T empleton in 1996 for live births resulting from IVF treatment. Data were us ed from the University Hospital, Nijmegen, The Netherlands, from March 1991 to January 1999. The predictive capacity of the model in our population di scriminated between those women with a low probability of success and those with a relatively high probability. Despite these encouraging findings, ou r data show that implementation of the model in clinical decision-making re mains difficult. The Templeton model is not applicable or usable in daily c linical practice, because the model did not give more information about the prognosis for the vast majority of the patients. Therefore, the search for better prognostic factors resulting in better predictive models should con tinue.