Searching for significance in TCR-cytoskeleton interactions

Authors
Caplan, S Baniyash, M
Citation
S. Caplan et M. Baniyash, Searching for significance in TCR-cytoskeleton interactions, IMMUNOL TOD, 21(5), 2000, pp. 223-228
Citations number
48
Categorie Soggetti
Immunology
Journal title
IMMUNOLOGY TODAY
ISSN journal
01675699 → ACNP
Volume
21
Issue
5
Year of publication
2000
Pages
223 - 228
Database
ISI
SICI code
0167-5699(200005)21:5<223:SFSITI>2.0.ZU;2-X
Abstract
Two T-cell receptor (TCR) populations are expressed on T cells; one is link ed to the cytoskeleton via its zeta chain. These cytoskeleton-linked recept ors (30-40% of the total number of TCRs) might be important in TCR-mediated signaling and/or concurrent events. Here, differences between the two popu lations are summarized, and new data are examined to speculate on the funct ional significance of cytoskeleton-linked TCRs.