Intraosseous xanthoma without lipid disorders - Case-report and literaturereview

A case of intraosseous xanthoma in a patient with a normal lipid profile is reported. Hyperlipidemia is present in most patients with xanthomas. Intra osseous xanthomas are rare, particularly in normolipidemic patients, in who m the presenting symptom is pain without skin lesions. A lytic lesion with a rim of sclerosis is seen on radiographs. Histology shows foam cells, gian t cells, and fibrosis. Intraosseous xanthoma is a benign tumor, and other d iagnoses must be ruled out (histiocytosis X, Erdheim Chester disease, clear cell carcinoma metastasis). Surgical excision of the lesion is the electiv e treatment. (C) 2000 Editions scientifiques et medicales Elsevier SAS.