Escherichia coli in phosphate-buffered saline irradiated with far-infrared
(FIR) energy was injured and killed even under the condition where the bulk
temperature of the suspension was maintained below the lethal temperature.
Using four kinds of antibiotics (penicillin G, chloramphenicol, nalidixic
acid and rifampicin), we investigated the Fin irradiation-induced damage to
E. coli on the basis of the sensitivity changes to the antibiotics. FIR ir
radiation increased the organism's sensitivity to rifampicin both below and
above the lethal temperature. The increase in sensitivity to chloramphenic
ol was observed only when FIR irradiation occurred above the lethal tempera
ture. These results suggest that the mechanism of FIR irradiation-induced d
eath in E. coli differs according to whether the radiation exposure occurs
above or below the lethal temperature.