Mortality, risk indicators of death, mode of death and symptoms of angina pectoris during 5 years after coronary artery bypass grafting in men and women

Citation
J. Herlitz et al., Mortality, risk indicators of death, mode of death and symptoms of angina pectoris during 5 years after coronary artery bypass grafting in men and women, J INTERN M, 247(4), 2000, pp. 500-506
Citations number
19
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
Journal title
JOURNAL OF INTERNAL MEDICINE
ISSN journal
09546820 → ACNP
Volume
247
Issue
4
Year of publication
2000
Pages
500 - 506
Database
ISI
SICI code
0954-6820(200004)247:4<500:MRIODM>2.0.ZU;2-S
Abstract
Aim. To describe mortality, risk indicators of death, mode of death and sym ptoms of angina pectoris during 5 years after coronary artery bypass grafti ng in women and men. Sample. All patients in western Sweden who underwent coronary artery bypass grafting without concomitant valve surgery and without previously performe d coronary artery bypass grafting between June 1988 and June 1991. Results. In all, 2000 patients participated in the evaluation, 381 (19%) of whom were women. Compared to men, who had a 5-year mortality of 13.3%, wom en had a relative risk of death of 1.4 (95% CI 1.0-1.8; P = 0.03). Renal dy sfunction interacted significantly (P = 0.048) with gender, in that the dif ferences were more marked in patients without renal dysfunction. When adjus ting for differences at baseline, the relative risk of death amongst women was 1.0 (95% CL 0.7-1.3). Compared to men, women had an increased risk of i n-hospital death and death associated with stroke. However, amongst the pat ients who died, the place and mode of death appeared to be similar in women and men. Amongst survivors after 5 years, women had more symptoms of angin a pectoris than men. Conclusion. During 5 years after coronary artery bypass grafting, women had an increased mortality compared to men; renal dysfunction seemed to intera ct with female gender regarding mortality. Women had a higher risk of in-ho spital death and death associated with stroke. However, the adjusted relati ve risk of death during 5 years was equal in women and men. Amongst survivo rs, women suffered more from angina pectoris than men.