Mortality, risk indicators of death, mode of death and symptoms of angina pectoris during 5 years after coronary artery bypass grafting in men and women
J. Herlitz et al., Mortality, risk indicators of death, mode of death and symptoms of angina pectoris during 5 years after coronary artery bypass grafting in men and women, J INTERN M, 247(4), 2000, pp. 500-506
Citations number
19
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
Aim. To describe mortality, risk indicators of death, mode of death and sym
ptoms of angina pectoris during 5 years after coronary artery bypass grafti
ng in women and men.
Sample. All patients in western Sweden who underwent coronary artery bypass
grafting without concomitant valve surgery and without previously performe
d coronary artery bypass grafting between June 1988 and June 1991.
Results. In all, 2000 patients participated in the evaluation, 381 (19%) of
whom were women. Compared to men, who had a 5-year mortality of 13.3%, wom
en had a relative risk of death of 1.4 (95% CI 1.0-1.8; P = 0.03). Renal dy
sfunction interacted significantly (P = 0.048) with gender, in that the dif
ferences were more marked in patients without renal dysfunction. When adjus
ting for differences at baseline, the relative risk of death amongst women
was 1.0 (95% CL 0.7-1.3). Compared to men, women had an increased risk of i
n-hospital death and death associated with stroke. However, amongst the pat
ients who died, the place and mode of death appeared to be similar in women
and men. Amongst survivors after 5 years, women had more symptoms of angin
a pectoris than men.
Conclusion. During 5 years after coronary artery bypass grafting, women had
an increased mortality compared to men; renal dysfunction seemed to intera
ct with female gender regarding mortality. Women had a higher risk of in-ho
spital death and death associated with stroke. However, the adjusted relati
ve risk of death during 5 years was equal in women and men. Amongst survivo
rs, women suffered more from angina pectoris than men.