The control group of a hospital-based case-control study on breast can
cer was used to assess the relationships between education, smoking ha
bits, alcohol consumption, and intake of selected macro- and micronutr
ients in Italian women. The study subjects were 2,588 women admitted t
o a network of hospitals in various Italian regions for nonneoplastic,
acute diseases unrelated to long-term changes in the diet. Although r
elatively few differences were observed, less educated subjects consum
ed more linoleic acid and polyunsaturated fats than did more educated
women. Smoking habits were associated with the largest differences in
selected antioxidant vitamins. Significant differences were observed f
or beta-carotene and vitamin C intake, with an 11% higher intake of be
ta-carotene and a 12% higher intake of vitamin C in ex-smokers than in
current smokers. Heavier alcohol drinkers tended to consume more reti
nol and iron but less beta-carotene than did moderate or nondrinkers.
Thus the differences in macro- and micronutrient intake were generally
moderate across categories of education, smoking, and alcohol consump
tion in this data set of Italian women. Nonetheless, they confirm the
importance of allowing for these variables in analyzing the relationsh
ip between nutritional factors and disease risk.