K. Naganobu et M. Hagio, Dose-related cardiovascular effects of isoflurane in chickens during controlled ventilation, J VET MED S, 62(4), 2000, pp. 435-437
We studied cardiovascular effects of isoflurane in chickens during controll
ed ventilation. Following the determination of the minimal anesthetic conce
ntration from the response to clamping of a digit, dose-related effect of i
soflurane on heart rate and arterial pressure were studied. The minimal ane
sthetic concentration of isoflurane was 1.25 +/- 0.13% (mean +/- SD, n=9).
There was a dose-dependent decrease in arterial pressure. The heart rate di
d not change significantly over a range of 1 to 2 times the minimal anesthe
tic concentration.