Anaplastic carcinoma of the pancreas with rhabdoid features

The malignant rhabdoid tumor (MRT) is histologically characterized by the i nvasive proliferation of polygonal to ovoid cells with abundant eosinophili c cytoplasm and eccentric vesicular nuclei with a prominent nucleolus, MRT frequently occurs in the kidney, but may also arise in other organs. Howeve r, MRT should be strictly distinguished from carcinomas with rhabdoid featu res, A post-mortem examination of a 68-year-old woman found an anaplastic c arcinoma of the pancreas with rhabdoid features displaying extensive invasi on into the neighboring tissues. To the best of our knowledge, this is the first case of a pancreatic tumor with rhabdoid features, Pathologists shoul d consider that carcinomas showing rhabdoid features may also appear in the pancreas. As pancreatic tumors with rhabdoid features have characteristic histopathological features and poor prognosis compared to other pancreatic tumors, careful histopathological differential diagnosis is important.