Phyllodes tumor of the prostate is rare. We have recently experienced a cas
e of phyllodes tumor of the prostate in a 57-year-old man who complained of
urinary retention for 1 year. The epithelial components were positive reac
tivity for prostate specific antigen. The stromal cells showed nuclear atyp
ia with increased mitotic activity. The tumor was diagnosed as a malignant
phyllodes tumor as it invaded into the urinary bladder and rectum, and grew
rapidly immediately after operation. We describe the morphological feature
s and immunohistochemical findings of malignant phyllodes tumor and review
the literature.