Ticlopidine plus aspirin for coronary thrombosis in Kawasaki disease

Selective inhibitors of the adenosine 5'-diphosphate pathway of platelet ac tivation have been used rarely in children in the United States. We report the successful use of ticlopidine, together with aspirin, in a 7-month-old infant with Kawasaki disease complicated by a thrombus in a giant coronary aneurysm that failed to resolve with thrombolytic therapy.