F. Sanchez-sancho et al., Efficient syntheses of polyannular heterocycles featuring microwave-accelerated Bischler-Napieralski reaction, stereoselective Heck cyclization, and Claisen rearrangement, SYNLETT, (4), 2000, pp. 509-513
We report the synthesis of the polyannular heterocyclic compounds 1-7. The
polyannular systems in the target molecules have been obtained using stereo
selective Heck reactions of suitable o-substituted iodoarenes. Additionally
, the first report on microwave-accelerated Bischler-Napieralski reaction i
s disclosed, which has been used in the syntheses of heterocycles 1-3. The
compound 7, bearing a quaternary stereogenic center, has been prepared thro
ugh a stereo-controlled Claisen-Johnson rearrangement from a derivative of
the allylic alcohol 25.