New cytotoxic isomalabaricane-type sesterterpenes from the New Caledonian marine sponge Rhabdastrella globostellata

Authors
Bourguet-Kondracki, ML Longeon, A Debitus, C Guyot, M
Citation
Ml. Bourguet-kondracki et al., New cytotoxic isomalabaricane-type sesterterpenes from the New Caledonian marine sponge Rhabdastrella globostellata, TETRAHEDR L, 41(17), 2000, pp. 3087-3090
Citations number
9
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
17
Year of publication
2000
Pages
3087 - 3090
Database
ISI
SICI code
0040-4039(20000422)41:17<3087:NCISFT>2.0.ZU;2-2
Abstract
Four new cytotoxic isomalabaricane sesterterpenes, aurorals 1-4, have been isolated from the New Caledonian marine sponge Rhabdastrella globostellata. Their structures were established by spectroscopic data including 1D and 2 D techniques. These compounds were found to exhibit cytotoxic activity on K B cells. (C) 2000 Elsevier Science Ltd. All rights reserved.