Synthesis of chiral dendrimers with a hydrocarbon backbone and applicationto the catalytic enantioselective addition of dialkylzincs to aldehydes

Authors
Sato, I Shibata, T Ohtake, K Kodaka, R Hirokawa, Y Shirai, N Soai, K
Citation
I. Sato et al., Synthesis of chiral dendrimers with a hydrocarbon backbone and applicationto the catalytic enantioselective addition of dialkylzincs to aldehydes, TETRAHEDR L, 41(17), 2000, pp. 3123-3126
Citations number
28
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
17
Year of publication
2000
Pages
3123 - 3126
Database
ISI
SICI code
0040-4039(20000422)41:17<3123:SOCDWA>2.0.ZU;2-#
Abstract
Chiral dendrimers with three or six beta-amino alcohols on hyperbranched hy drocarbon chain-ends were synthesized. These macromolecules can act as chir al catalysts for the enantioselective addition of dialkylzincs to aldehydes . The corresponding secondary alcohols are obtained in high enantiomeric ex cess (up to 86% e.e.). (C) 2000 Elsevier Science Ltd. All rights reserved.