Importance of ultrasonography in early detection of renal cell carcinoma

Citation
S. Siemer et al., Importance of ultrasonography in early detection of renal cell carcinoma, UROLOGE A, 39(2), 2000, pp. 149-159
Citations number
35
Categorie Soggetti
Urology & Nephrology
Journal title
UROLOGE A
ISSN journal
03402592 → ACNP
Volume
39
Issue
2
Year of publication
2000
Pages
149 - 159
Database
ISI
SICI code
0340-2592(200003)39:2<149:IOUIED>2.0.ZU;2-S
Abstract
The importance of ultrasonography in early detection of renal cell carcinom a was analyzed for 1854 patients,who were operated from 1975 to 1997. The i i-year survival rate of all patients amounts to 75%, the 10- and 20-year su rvival rate was 68% and 64%. While from 1975 to 1986 tumor symptoms like he maturia (30%),abdominal pain (19%) and palpabele mass (3%) lead to diagnosi s of renal cell carcinoma in 56% of all cases, there were only 26% from 198 7 to 1997. 83% of asymtomatical tumors from 1987 to 1997 were accidentally detected by means of ultrasonography in a kidney independent examination. T hese rumors are significantly smaller (5,5 cm) than the tumors of symptomat ical patients (7,8 cm) and show often a significantly lower local tumor sta ge, a better tumor grade, frequently lymph nodes, which are free of tumor i nfiltration and more rarly distant metastasis. The 5-year survival rate of patients with incidental tumors, detected by ul trasonography (82%) was significantly better (log rank <0,001) in compariso n with the symptomatical patients (72%). These results verify 1. The effectivity of ultrasonography in early diagnos is of renal cell carcinoma and 2. The advantage of survival on patients wit h early tumor detection. That's why asymptomatic patients, who selected und er risk factors should be examinated by ultrasonography consistently too.