The author's institution decided to improve its management of H-2 anta
gonist use by concentrating on maximizing timely IV-to-oral conversion
of two medications rather than driving use of a single preferred agen
t. After more modest initiatives failed to yield sufficient rates of I
V-to-oral conversion in appropriate patients, the institution implemen
ted a program in which pharmacists monitor patients on IV H-2 antagoni
sts and automatically switch them to oral formulations when appropriat
e. This article describes the program's rationale and reports its resu
lts.