F. Bosch-princep et al., Fine needle aspiration and touch imprint cytology of a malignant fibrous histiocytoma of the spermatic cord - Case report, ACT CYTOL, 44(3), 2000, pp. 423-428
Citations number
18
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology","Medical Research Diagnosis & Treatment
BACKGROUND: No cytologic reports on spermatic cord sarcomas have been publi
shed.
CASE: A 64-year-old man presented with a slowly growing, painless, left spe
rmatic cord enlargement. Fine needle aspiration (FNA) obtained <1 mt of blo
ody fluid consisting of solitary, markedly anaplastic and pleomorphic tumor
giant cells occasionally arranged in small fragments. Rare atypical spindl
e cells could be observed. Some reactive lymphocytes were observed intermin
gled with tumor cells. Immunohistochemistry displayed vimentin reactivity a
nd negativity for keratins and leukocytic common antigen. The specimen remo
ved showed a well-circumscribed, 30-mm, yellowish solid tumor. Touch imprin
ts displayed pleomorphic tumor cells showing intense anisonucleosis; a mode
rate amount of clear, sometimes microvacuolated cytoplasm; and tissue fragm
ents With a storiform pattern. Histologic examination revealed microscopic
and immunohistochemical features of malignant fibrous histiocytoma (MFH) ar
ising in soft tissues of the spermatic cord.
CONCLUSION: FNA of It spermatic cord lesion may reveal a pleomorphic sarcom
a. A pleomorphic appearance together with some spindle elements and compati
ble immunocytochemistry could help diagnose spermatic cord MFH. This is one
of the few reports dealing with FNA cytology of paratesticular tumors and
the first report, to the best of our knowledge, showing the cytologic chara
cteristics of a case of spermatic cord MFH.