Hot eluent capillary liquid chromatography using zirconia and titania based stationary phases

High speed capillary liquid chromatographic separations using a simple home made system constructed from readily available inexpensive components have been studied. Usings thermally stable zirconia and titania based packing, the separation of eight alkylbenzene derivatives in less than 2 min is show n. The system is capable of operating at temperatures as high as 200 degree s C and pressures up to 10,000 psi and can, thus, take advantage of the red uction in eluent viscosity and enhanced mass transport at elevated temperat ures to operate at very high linear velocities without sacrificing separati on efficiency (C) 2000 Elsevier Science B.V. All rights reserved.