We prospectively evaluated the frequency, time-course and predisposing
factors of phantom eye syndrome in 53 patients who underwent surgical
eye amputation to cure ocular cancer. Before surgery, patients were c
lassified as Group I (n=25) if they had no history of headache or Grou
p II (n=28) if they were headache sufferers. Three clinical patterns w
ere distinguished: phantom pain, non-painful phantom phenomena and pho
topsias. Their symptoms developed 7 days to 6 months after surgery, wi
th peak incidence after 6 months (photopsia 43%; phantom pain 28%; non
-painful phantom phenomena 62%). Phantom eye syndrome was more common
in headache sufferers than in non-headache subjects. Headache sufferer
s were more prone to phantom pain, but more so to non-painful phenomen
a and photopsias. These findings are in accord with our previous resul
ts indicating that primary headache sufferers are prone to phantom too
th pain.