Identification of six CAG repeat domains into the human chromosomic region12q24.1

Six different domains of CAG repeats from a human chromosome 12 specific co smid library were identified, cloned, and sequenced. These CAG repeat domai ns were localized into the human chromosomic region 12q24.1. Five of them c onstitute repeat candidates for expansions in autosomal dominant neurologic al disorders with genetic anticipation, and they can also contribute to the chromosome walking in the human genome project. (C) 2000 Academic Press.