Dental manifestations in severe combined immunodeficiency following bone marrow transplantation

Authors
Cole, BOI Welbury, RR Bond, E Abinun, M
Citation
Boi. Cole et al., Dental manifestations in severe combined immunodeficiency following bone marrow transplantation, BONE MAR TR, 25(9), 2000, pp. 1007-1009
Citations number
12
Categorie Soggetti
Hematology,"Medical Research Diagnosis & Treatment
Journal title
BONE MARROW TRANSPLANTATION
ISSN journal
02683369 → ACNP
Volume
25
Issue
9
Year of publication
2000
Pages
1007 - 1009
Database
ISI
SICI code
0268-3369(200005)25:9<1007:DMISCI>2.0.ZU;2-B
Abstract
Severe combined immunodeficiency (SCID) is a rare primary immunodeficiency disorder with an estimated overall frequency of 1 in 75 000 live births. Bo ne marrow transplantation is the only curative treatment available. Using T cell-depleted HLA non-identical bone marrow requires preconditioning with a short course of cytotoxic chemotherapy. We report severe dental developme ntal anomalies in three such patients under longterm follow up.