Medical management of Beauveria bassiana keratitis

Purpose. To describe a case of Beauveria bassiana keratitis and to discuss the management of this rare condition. Methods. Pin 82-year-old woman under went surgical repair of a graft wound dehiscence. Seven months later, short ly after the removal of sutures, the patient developed a fungal keratitis. B. bassiana was identified as the infecting organism. The patient was treat ed with topical natamycin and oral fluconazole. Results. Following antifung al therapy, the corneal ulcer was eradicated, but the patient underwent rep eat penetrating keratoplasty for decreased vision due to corneal edema. The graft remains clear and visual acuity is substantially improved. Conclusio n. The medical management of B. bassiana keratitis has previously been unsu ccessful. The use of topical natamycin combined with oral fluconazole in th e management of this case is discussed.