Two genes recently identified in Arabidopsis thaliana may be involved in se
questering free copper ions in the cytoplasm and delivering copper to post-
Golgi vesicles. The genes COPPER CHAPERONE and RESPONSIVE TO ANTAGONIST1 ar
e homologous to copper-trafficking genes from yeast and humans. This plant
copper-delivery pathway is required to create functional ethylene receptors
. The pathway may also facilitate the transport of copper from senescing le
af tissue. In addition, several other genes have been identified recently t
hat may have a role in copper salvage during senescence.