Aim: Macular branch retinal vein occlusion (MBRVO) is a subgroup of branch
retinal vein occlusion in which the occlusion is limited to a small venous
vessel draining a sector of the macular region. The present study aims to e
valuate the efficacy of grid laser treatment for macular edema in MBRVO. Me
thods: 77 Patients with MBRVO of recent onset were prospectively studied du
ring a 24 month period. Eyes were randomly assigned to a grid laser treatme
nt group and to a control group. Clinical parameters such as visual acuity,
presence of macular edema and angiographic features were recorded during t
he follow-up period. Results: Visual acuity increased significantly in both
groups after 3 months of follow-up (p < 0.001) and after 1 year of follow-
up (p < 0.005). No additional improvement was noted at the two year control
. There was no statistical difference between the two groups. Conclusions:
The visual prognosis of MBRVO is not improved after grid laser treatment of
macular edema. This suggests that sudden ischemic damage to central photor
eceptors rather than macular edema is the main factor for permanent visual
acuity reduction.