Applications of capillary electrophoresis with electrochemical detection in pharmaceutical and biomedical analyses

As a high efficiency separation technique, capillary electrophoresis has be en widely used in various fields of analytical science. This review discuss es the applications of electrochemical detection systems combined with capi llary electrophoresis in pharmaceutical and biomedical analysis. These dete ction methods mainly involve amperometric detection but also include conduc tivity detection and potentiometric detection. Its applications in the fiel d are divided into six parts, including catechol compounds, thiols, amino a cids and peptides, carbohydrates, general pharmaceuticals, and other relate d compounds. A relatively detailed discussion is described for each compoun d under the current studied. On this basis, we have suggested several conce ivable directions for capillary electrophoresis with electrochemical detect ion in the future.