This study was conducted to assess whether female mortality from lung cance
r is associated with residence in communities adjacent to a petroleum refin
ery plant and whether petroleum air pollution could affect the sex ratios o
f births. The Kaohsiung Refinery of the Chinese Petroleum Corp. is the olde
st oil refinery in Taiwan and is located between the Tso-Ying and the Nan-T
zu municipalities. Standardized mortality ratios (SMRs) for female lung can
cer and sex ratios of births were calculated for each municipality for the
years 1971-1996. Cumulative-sum techniques were used to detect the occurren
ce of changes in the SMRs. The study results show that mortality from femal
e lung cancer rose gradually about 30 to 37 years after the operation of a
petroleum refinery plant began. However, the association between exposure t
o the petroleum air pollution and abnormal sex ratios at birth was not sign
ificant. (C) 2000 Academic Press.