Heterologeous mullerian mixed tumor after whole body irradiation because of Hodgkin's disease in stage IV

Purpose: With an incidence of 1.5% of all malignant diseases of the uterus as specified in the literature, the mullerian mixed tumor is a rarity among st the malignancies of the female genital tract. Methods: A retrospective analysis of an individual case report with the occ urrence of heterologous mullerian mixed tumor years after irradiation becau se of Hodgkin's disease. Results: This case reports describes the occurrence of a mullerian mixed tu mor 12 years after the treatment of Hodgkin's disease by whole body irradia tion. To our knowledge, the incidence of a mullerian mixed tumor after the treatment of Hodgkin's disease has rarely been described up to now in the l iterature. Conclusion: This case report appears to indicate the possible carcinogenic potency of radiotherapy when administered many years before. A causal conne ction between the administration of whole body irradiation and the developm ent of a mullerian mixed tumor cannot be established.