A convenient synthetic route to polyether-tagged cyclam ligands and their nickel derivatives

Authors
Bellouard, F Chuburu, F Yaouanc, JJ Handel, H Le Mest, Y
Citation
F. Bellouard et al., A convenient synthetic route to polyether-tagged cyclam ligands and their nickel derivatives, EUR J ORG C, (12), 1999, pp. 3257-3261
Citations number
22
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
ISSN journal
1434193X → ACNP
Issue
12
Year of publication
1999
Pages
3257 - 3261
Database
ISI
SICI code
1434-193X(199912):12<3257:ACSRTP>2.0.ZU;2-I
Abstract
A specific strategy is described for the synthesis of stable polyethylene o xide tagged tetraazamacrocycles (PEO-cyclam) in five steps (overall yields for 12 and 13 48% and 22%, respectively). Various attempts via classical pa thways demonstrated: (1) the low reactivity of PEO derivatives, and (ii) th e necessity of a stabiliser arm between the cyclam and the PEO chain. Nicke l complexes have been prepared and characterised by electrochemistry.