A new synthetic approach toward (+)-ambruticin analogs: Preparation of a C10-C11 cis-isomer fragment

Authors
Michelet, V Adiey, K Bulic, B Genet, JP Dujardin, G Rossignol, S Brown, E Toupet, L
Citation
V. Michelet et al., A new synthetic approach toward (+)-ambruticin analogs: Preparation of a C10-C11 cis-isomer fragment, EUR J ORG C, (11), 1999, pp. 2885-2892
Citations number
40
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
ISSN journal
1434193X → ACNP
Issue
11
Year of publication
1999
Pages
2885 - 2892
Database
ISI
SICI code
1434-193X(199911):11<2885:ANSAT(>2.0.ZU;2-#
Abstract
A new methodology has been applied to synthesize an isomer of the west part of (+)-ambruticin based on an efficient asymmetric de novo access to the A unit and sequential stereospecific reactions catalyzed by Pd-0 for the con struction of the B unit.