Long-term disease-free acute myeloblastic leukemia with inv(16) is associated with PCR undetectable CBF beta/MYH11 transcript

Authors
Martinelli, G Ottavlani, E Testoni, N Montefusco, V Buonamici, S Tura, S
Citation
G. Martinelli et al., Long-term disease-free acute myeloblastic leukemia with inv(16) is associated with PCR undetectable CBF beta/MYH11 transcript, HAEMATOLOG, 85(5), 2000, pp. 552-554
Citations number
10
Categorie Soggetti
Cardiovascular & Hematology Research
Journal title
HAEMATOLOGICA
ISSN journal
03906078 → ACNP
Volume
85
Issue
5
Year of publication
2000
Pages
552 - 554
Database
ISI
SICI code
0390-6078(200005)85:5<552:LDAMLW>2.0.ZU;2-7
Abstract
This study investigates the benefits of minimal residual disease in a subse t of AML patients with inv(16) by means of non-quantitative detection of CB F beta/MYH11 fusion transcript. We found that CBF beta/MYH11 RT-PCR negativ ity is associated with cure of disease.