Objective: We report rates and causes of death for a cohort of 246 eating d
isordered women and provide descriptive information on their eating disorde
r and comorbid diagnoses Method: Data on mortality were collected as part o
f a longitudinal study of anorexia nervosa and bulimia nervosa, now in its
11th year. Of her data sources included death certificates, autopsy reports
, relative interviews, and a National Death Index search. Results: Seven de
aths have occurred during the study, all among anorexic subjects with a his
tory of binging and purging and with comorbid Axis I disorders. The crude m
ortality rate was 5.1%. The standardized mortality ratios for death (9.6) a
nd suicide (58.1) were significantly elevated (p <.001). Conclusions: Anore
xia nervosa is associated with a substantial risk of death and suicide. Fea
tures correlated with fatal outcome are longer duration of illness, binging
and purging, comorbid substance abuse, and comorbid affective disorders. (
C) 2000 by John Wiley & Sons, Inc.