Epilepsy surgery candidates with extratemporal foci represent a particular
diagnostic and therapeutic challenge, because of anatomic and functional fe
atures of the pertaining areas. In the last decade, novel developments in t
he field of electrophysiological techniques have offered new approaches to
detailed localization of specific epileptic discharges as well as eloquent
regions. Magnetoencephalography, in combination with neuroimaging data and
simultaneously recorded EEG, yields promising results to clarify centers of
epileptic activity and their relationship to structural abnormalites and f
unctionally significant areas. Examples are given to illustrate the range o
f applications of this method as a contribution to routine presurgical eval
uation.