Objective: This article reviews the available data on social functioning in
depression and provides clinical guidelines and opinion on this important
and expanding field.
Data sources: A MEDLINE search was conducted to identify all English-langua
ge articles (1988-1999) using the search terms depression and social functi
oning, depression and social adjustment, depression and psychosocial functi
oning, and social functioning and antidepressant. Further articles were obt
ained from the bibliographies of relevant articles.
Data synthesis: Depressive disorders are frequently associated with signifi
cant and pervasive impairments in social functioning, often substantially w
orse than those experienced by patients with other chronic medical conditio
ns. The enormous personal, social, and economic impact of depression, due i
n no small part to the associated impairments in social functioning, is oft
en underappreciated. Both pharmacologic and psychotherapeutic approaches ca
n improve social impairments, although there is a lack of extended, randomi
zed controlled trials in this area using consistent assessment criteria.
Conclusion: Despite this lack, it is becoming clear that not all treatments
are equally effective in relieving the impaired social functioning associa
ted with depressive disorders. Furthermore, efficacy in relieving the core
symptoms of depression does not necessarily guarantee efficacy in relieving
impaired social functioning.