Bt. Levy et al., Is paracervical block safe and effective? A prospective study of its association with neonatal umbilical artery pH values, J FAM PRACT, 48(10), 1999, pp. 778-784
BACKGROUND. Paracervical blocks (PCBs) relieve labor pain, but reports of a
ssociated complications have caused many physicians to question their safet
y.
METHODS. We designed a prospective observational study to examine the assoc
iation between PCBs and umbilical artery hydrogen ion concentration (pH) va
lues. A total of 261 healthy women in labor were recruited from a community
hospital. Physicians used 1% lidocaine for the PCBs. We used multivariate
linear regression to model predictors of umbilical artery pH at birth.
RESULTS. Of the women studied, 238 (91%) received analgesia during labor (n
albuphine, PCB, pudendal, caudal, or epidural). Of these, 126 (48%) receive
d at least one PCB (191 were given), and 197 (76%) received at least one do
se of nalbuphine (237 were given). Univariate analyses showed no significan
t differences in mean I-minute Apgar scores, 5-minute Apgar scores, umbilic
al artery pH, resuscitation with oxygen by mask, or length of newborn stay
according to either PCB or nalbuphine exposure. Factors significantly assoc
iated with lower umbilical artery pH in a linear regression analysis includ
ed longer second stage of labor (-0.032 pH units for each I-hour increase;
95% confidence interval [CI], -.046 to -.018), pudendal block (-0.022; 95%
CI, -.040 to -.004), intrauterine pressure catheter use (-0.029; 95% CI, -0
.053 to -.006), nuchal cord (-0.027; 95% CI, -.051 to -.004), and midforcep
s delivery (-0.080; 95% CI, -.159 to.000). Increasing maternal age and indu
ction with either artificial rupture of membranes or gel were associated wi
th higher umbilical artery pH values.
CONCLUSIONS. After adjusting for other variables, neither PCB nor nalbuphin
e use were associated with umbilical artery pH at birth. PCBs using 1% lido
caine injected superficially should be considered a safe and effective form
of obstetric analgesia. PCBs may be especially useful for women giving bir
th in hospitals where other obstetric anesthesia services are not readily a
vailable.