Infrared spectroscopic studies of nanoscale iron oxide deposits isolated from human thalassemic tissues

Authors
Chua-anusorn, W Webb, J
Citation
W. Chua-anusorn et J. Webb, Infrared spectroscopic studies of nanoscale iron oxide deposits isolated from human thalassemic tissues, J INORG BIO, 79(1-4), 2000, pp. 303-309
Citations number
33
Categorie Soggetti
Biochemistry & Biophysics","Inorganic & Nuclear Chemistry
Journal title
JOURNAL OF INORGANIC BIOCHEMISTRY
ISSN journal
01620134 → ACNP
Volume
79
Issue
1-4
Year of publication
2000
Pages
303 - 309
Database
ISI
SICI code
0162-0134(200004)79:1-4<303:ISSONI>2.0.ZU;2-1
Abstract
Ferritin and hemosiderin isolated from human thalassemic tissues have been characterized by infrared spectroscopy. Spectral features due to both the o rganic components and the inorganic iron oxyhydroxide have been identified. In particular, spectral evidence for the presence of the goethite (alpha-F eOOH) form of hemosiderin has been obtained in the < 800 cm(-1) range. Vari ous treatments of the hemosiderin isolates result in only small changes in the infrared spectrum indicating the close association of the organic compo nents with the nanoscale iron particles present. (C) 2000 Elsevier Science Inc. All rights reserved.