Unusual health problems have been reported by Gulf War (GW) veterans, but n
o single etiology has been linked to these illnesses. This study was conduc
ted to determine the association between self-reported GW deployment stress
ors and an illness defined by a combination of fatigue, mood-cognition, and
musculoskeletal symptoms. A total of 1002 GW veterans from this cross-sect
ional survey of fc,ur Air Force units completed a self-administered questio
nnaire that asked about symptoms, demographic and military characteristics,
and stressors during deployment. Severe and mild-moderate illness was posi
tively associated with self-reports of pyridostigmine bromide use, insect r
epellent use and belief in a threat from biological or chemical weapons. In
juries requiring medical attention were only associated with severe illness
. 'These results suggest a link between self-reported chemical, emotional,
and physical exposures, and GW veterans' illness. Further research is neede
d to determine physiological and psychological mechanisms through which suc
h stressors could have contributed to this symptom complex.