The pharmacologic mechanism by which inhaled epinephrine reduces airway obstruction in respiratory syncytial virus-associated bronchiolitis

Authors
Barr, FE Patel, NR Newth, CJL
Citation
Fe. Barr et al., The pharmacologic mechanism by which inhaled epinephrine reduces airway obstruction in respiratory syncytial virus-associated bronchiolitis, J PEDIAT, 136(5), 2000, pp. 699-700
Citations number
9
Categorie Soggetti
Pediatrics,"Medical Research General Topics
Journal title
JOURNAL OF PEDIATRICS
ISSN journal
00223476 → ACNP
Volume
136
Issue
5
Year of publication
2000
Pages
699 - 700
Database
ISI
SICI code
0022-3476(200005)136:5<699:TPMBWI>2.0.ZU;2-X
Abstract
Inhaled racemic epinephrine relieves airway obstruction in patients with re spiratory syncytial virus bronchiolitis. The contribution of alpha- versus beta- adrenoreceptor stimulation toward this clinical effect is unknown. We describe an infant treated with propranolol for supraventricular tachycard ia in whom respiratory syncytial virus bronchiolitis developed. Inhaled rac emic epinephrine improved his respiratory symptoms, whereas nebulized albut erol did not.