Solid facial edema preceding a diagnosis of retro-orbital B-cell lymphoma

Persistent solid facial edema is a rare condition of unknown cause. Althoug h acute facial edema has been associated with numerous disease processes su ch as infections, neoplasms, immune disorders, inflammation, neuropathic pr ocesses, drugs, mechanical obstructions, and trauma, solid facial edema has most often been associated with acne vulgaris. We report the first case, t o our knowledge, of solid facial edema preceding a diagnosis of a subcutane ous scalp and orbital/periorbital B-cell lymphoma.