A 10-year-old Great Pyrenees was presented for anorexia and weight loss, On
physical examination, the dog was emaciated and showed a large ulcerated l
esion on the right lower lip in addition to an enlarged right testicle. Fin
e-needle aspiration biopsy of the testicle and surgical biopsy of the lip l
esion were performed; the histopathological report was consistent with meta
static seminoma. The diagnostic and therapeutic approach in this unusual me
tastatic seminoma is presented and compared to the previous literature, A m
ultimodality therapy consisting of surgery and chemotherapy is proposed for
the clinical management of metastatic seminoma in dogs.