Citation
Ttt. Bui et al., TOAC: a useful C-alpha-tetrasubstituted alpha-amino acid for peptide conformational analysis by CD spectroscopy in the visible region. Part I, J CHEM S P2, 5, 2000, pp. 1043-1046
Citations number
23
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2
ISSN journal
03009580
→ ACNP
Volume
5
Year of publication
2000
Pages
1043 - 1046
Database
ISI
SICI code
0300-9580(200005)5:<1043:TAUCAA>2.0.ZU;2-G
Abstract
Doubly labelled 4-amino-4-carboxy-2,2,6,6-tetramethylpiperidine-1-oxyl (TOA
C)-containing trichogin analogues showed a correlation between the CD inten
sity of the TOAC transition and their conformation. The helical-inducing pr
operty of the TOAC residue is position dependent and, apart from the N-term
inal position, better than that of Aib.