Rs. Foster et Jp. Donohue, Retroperitoneal lymph node dissection for the management of clinical stageI nonseminoma, J UROL, 163(6), 2000, pp. 1788-1792
Purpose: We review the rationale for the use of retroperitoneal lymph node
dissection for clinical stage I nonseminomatous testis cancer.
Materials and Methods: The published literature regarding the alternative t
reatments for clinical stage I nonseminoma was reviewed as well as the pers
onal experience of the authors to define the role of retroperitoneal lymph
node dissection.
Results: Retroperitoneal lymph node dissection alone is curative in 50% to
75% of patients with pathological stage II disease. The only significant lo
ng-term morbidity is a 1% chance of small bowel obstruction. If recurrence
develops after retroperitoneal lymph node dissection, it is virtually alway
s curable with cisplatin based chemotherapy.
Conclusions: Retroperitoneal lymph node dissection retains a therapeutic an
d staging capability in these patients. The probability for cure, short and
long-term morbidity, and minimal need for long-term followup in these pati
ents indicates that retroperitoneal lymph node dissection continues to be s
tandard therapy for clinical stage I nonseminoma.