Self-injection ictal SPECT during partial seizures

The authors compared ictal SPECT injection performed by medical personnel w ith self-injection ictal SPECT in six patients with refractory temporal lob e epilepsy. Self-injection was safe and started faster. Self-injection subt raction ictal SPECT coregistered to MRI (SISCOM) was localizing in three pa tients who had a complex partial seizure, but only one of three patients wh o had a simple partial seizure, which may limit its usefulness in clinical practice. The localizing information of self-injection was better in three patients, and obviated the need for depth-EEG studies in one patient.