Synthesis of bis- and oligo-gem-difluorocyclopropanes using the olefin metathesis reaction

[GRAPHICS] Synthesis of six types of novel bis and oligo-gem-difluorocyclopropanes has been accomplished through the olefin metathesis reaction protocol. Two typ es of ruthenium based olefin metathesis catalysts were tested: the rutheniu m catalyst coordinated with 1,3-dimesityl-4,5-dihydrolmidazol-2-ylidene and tricyclohexylphosphine ligands gave better results than the ruthenium cata lyst that coordinated with two tricyclohexylphosphine ligands.