An 8-year-old boy developed vomiting and severe headache following minor he
ad trauma. A CT scan of the head demonstrated a lytic lesion of the skull a
nd adjacent epidural hematoma. Surgical evacuation and removal of the skull
lesion and hematoma were carried out, and pathologic evaluation resulted i
n a diagnosis of Langerhans' cell histiocytosis (LCH). Epidural involvement
of Langerhans' cell histiocytosis is very rare, and we report the first ca
se of LCH presenting as an intracranial epidural hematoma.